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Tubulus (Latin) - A small pipe
8 terms share this root
Acute tubular necrosis

A "sharp" or quickly onset "death" of the "small pipes" within the kidney.

  • Acuere (Latin) - To Sharpen, sharply onset
  • Tubulus (Latin) - A small pipe
  • Nekros (Greek) - Dead body, Corpse, Death
  • Injury of the renal tubular epithelial cells, with dead cells clogging the tubules and resulting in obstruction
  • Brown casts
  • Failure to concentrate urine
  • Intrarenal azotemia
  • Causes include ischemia, aminoglycosides, heavy metals, myoglobinuria, ethylene glycol, contrast dye, and urate
  • Microtubule

    "Small" "tube" composed of a helical array of polymerized dimers of alpha and beta tubulin.

    • Mikros (Greek) - Small, little, petty, trivial, slight
    • Tubulus (Latin) - A small pipe
  • ChediakHigashi syndrome
  • Incorporated into cilia, flagella, mitotic spindles
  • Grows slowly collapses quickly
  • Peritubular capillary beds

    "Hair" like vessels found "around" the "pipes" of the kidney.

    • Peri (Greek) - Around, about, beyond
    • Tubulus (Latin) - A small pipe
    • Capillus (Latin) - Hair
    • Bed (Old English) - Bed
  • Creation of concentration gradients in the kidney
  • Release of erythropoietin in response to hypoxia
  • Function of reabsorption and secretion of electrolytes and other molecules
  • Proximal convoluted tubule

    The "nearest" "intertwined" "pipe" of the functional unit of the kidney.

  • First segment of the nephron that includes Bowman's capsule
  • Location where many solutes, including glucose, are reabsorbed
  • Rel Cell Carcinoma, Acute Tubular Necrosis
  • Renal tubular acidosis

    "A condition or disease" relating to the "small pipes" or tubules of the "kidneys" being unable to secrete "acid" or reabsorb base (bicarbonate)

    • Renes (Latin) - Kidneys
    • Tubulus (Latin) - A small pipe
    • Acidus (Latin) - Relating to acid
    • Osis (Greek) - A condition, disease
    Seminiferous tubules

    "Tubelike" structures in the testes which "bear" or "carry" the "seed"

  • Location where gametes are created in the testes through meiosis. Formed from primitive sex chords.
  • Tuberculosis

    A very complex "disease" involving the "small pipes" of the lungs.

    • Tubulus (Latin) - A small pipe
    • Osis (Greek) - A condition, disease
  • Classic cause of Caseating granulomas
  • Grows slowly and often uses LowensteinJensen agar
  • Classic clinical presentation of fever, weight loss, hemoptysis, and night sweats
  • Around 460 BC, Hippocrates described Phthisis (Greek for consumption, an old word for pulmonary tuberculosis, as the most widespread disease of the times. Before the Industrial Revolution, in folklore, it was believed that TB was associated with vampires because when one family member died, the other infected members lost health slowly, almost as if the original member was slowly draining the life out of the family members.

  • Medytoons

    • A 33 year old incarcerated man with medical history significant for asthma is brought to the prison physician for complaint of ongoing productive cough. The patient reports that over the last few weeks, he has been coughing vigorously and bringing up green sputum, often times tinged with blood. On further investigation, the patient also discloses that he has lost 10 lbs in the last few weeks since the coughing began, and that he has occasionally been waking up drenched in sweat. Physical exam is significant for productive cough, and rhonchi appreciated over the left lung field. What type of lesion and where is most likely to be present on X-ray of this patient's lung?

    USMLE Step 1

    Tubulointerstitial nephritis

    "Inflammation" of the "small pipes" in the "kidneys."

    • Tubulus (Latin) - A small pipe
    • Interstitium (Latin) - Interval, space between
    • Nephros (Greek) - Kidney
    • Itis (Greek) - Inflammation, pertaining to disease
  • Can be caused by NSAIDs, sulfonamides, penicillins
  • Associated with eosinophilic pyuria
  • Can be asymptomatic