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Soma (Greek) - Body
16 terms share this root
Autosomaldominant hyperIgE syndrome (Job syndrome)

Immune disease due to a mutation in Th17 cell leading to impaired recruitment of neutrophils to sites of infection, allowing for opportunistic infections.

  • Auto (Greek) - Self, one's own
  • Soma (Greek) - Body
  • Domint (Latin) - Ruling
  • Hyper (Greek) - Over, beyond, excess
  • Immunis (Latin) - Free, exempt
  • Globus (Latin) - Sphere, globe
  • Syn (Greek) - With, together
  • Droma (Greek) - Running, A Course
  • Presentation: FATED: course Facies, noninflamed staphylococcal Abscess, retained primary Teeth, increased IgE, Dermatologic problems (eczema)
  • The disease is med after the biblical character Job, whose body was covered with boils by Satan
  • Lysosome

    A cellular "body" involved in "loosening" or destruction of ingested material by the cell.

    • Lysis (Greek) - Destruction, A loosening, setting free, releasing, dissolution
    • Soma (Greek) - Body
  • The organelle works at a lower pH than normal
  • Lysosomal storage diseases include TaySachs, Gaucher, NiemannPick, Fabry, Hunter, Hurler, Krabbe, Metachromatic leukodystrophy, and Icell disease
  • Macrosomia

    The condition of having a "large" "body".

    • Makros (Greek) - Large, large to scale
    • Soma (Greek) - Body
  • A condition of newborns commonly seen in mothers with uncontrolled diabetes
  • Sometimes referred to as LGA or large for gestational age
  • Considered to be macrosomic if the baby weighs more than 4500 grams, or 9lbs 15oz
  • Mammillary bodies

    A pair of small "breastshaped" "bodies" in the brain involved in the limbic system.

  • Damaged in WernickeKorsakoff syndrome, which is seen in alcoholics
  • Associated with thiamine deficiency
  • Nucleosome

    Part of the chromatin structure in which loops of D wrap around histone proteins to make "kernels" forming compact "bodies" of D.

  • Beads on a string
  • Phagosome

    A "body" formed within a cell after "eating" a molecule or another cell.

  • An intracellular body formed after phagocytosis of something external to the phagocyte.
  • Usually combines with lysosomes for destruction and/or processing
  • Impaired phagolysosome formation in ChediakHigashi syndrome.
  • Schistosoma hematobium

    Parasite that "specifically lives" in the "blood" networks around the bladder. It looks like it has a "divided" "body" under a microscope.

    • Schistos (Greek) - Divided, deparated
    • Soma (Greek) - Body
    • Haima (Greek) - Blood
    • Bium (New Latin) - Organism having specific mode of life
  • Major agent of Schistosomiasis found mostly in the Middle East and Africa. Causes hematuria and fibrosis of the bladder
  • This results from adults populating the venous plexuses of the bladder releasing eggs into the wall of the bladder.
  • Squamous cell carcinoma
  • Hematuria
  • Praziquantel
  • Schistosomiasis was first described by Theodor Biharz in 1851 while working at the KasrelAini hospital in Cairo. He discovered the trematode during a postmortem examination.
  • Schistosoma Mansoni

    Parasite that looks it has a "divided" "body" under a microscope. It is a major cause of Schistosomiasis, specifically causing intestinal schistosomiasis.

  • Most widespread of the schistosomiasiscausing agents.
  • Poor sanitation/cercariainfected waters results in swimmer's itch
  • Enlarged gastrointestinal/abdominal organs from eggs lodging
  • Praziquantel
  • S. mansoni is med after Sir Patrick Manson who first identified it in Formosa (Taiwan).
  • Somatic hypermutation

    A mechanism for cells to create "exceeding" amounts of "changes" or mutations in certain immune cells, that takes place in the "body"

    • Soma (Greek) - Body
    • Hyper (Greek) - Over, beyond, excess
    • Mutare (Latin) - To change
  • A cellular mechanism of B cells to create diversity among cellular receptors that react to foreign antigens involving a series of mutations in the variable regions of immunoglobulin genes
  • Somatoform disorder

    A "not" "regular" psychiatric condition in which a person feels like there "body" takes "form" of disease or problem, despite nothing actually being wrong.

    • Soma (Greek) - Body
    • Forma (Latin) - Form
    • Dis (Latin) - Not, In a Different Direction, Between
    • Ordinare (Latin) - Ordain, regular
  • A psychiatric illness in which patients experience and feel symptoms that are not specifically caused by a medical condition
  • Patients with somatoform disorder will present with vague symptoms that cannot be traced to a specific medical finding, positive test results, or pathophysiology of an illness.
  • Somatomedin

    A hormone "inside" the "body" that acts to stimulate tissue growth

    • Soma (Greek) - Body
    • Internus (Latin) - Interl, inside, inward, within
  • Hormones that act to stimulate tissue growth
  • Stimulated by growth hormone and stimulate the production of somatostatin
  • Insulin like growth factor is a somatomedin
  • Often released from the liver
  • Somatostatin

    Inhibitory, or "stationary", hormone in the "body" made in the brain, delta cells of pancreas, stomach and intestines

    • Soma (Greek) - Body
    • Statos (Greek) - Standing, statiory
  • Inhibitory peptide hormone
  • Octreotide is a somatostatin analog
  • Suppresses the release of gastric hormones, decreases the rate of gastric emptying
  • Has negative feedback effects on the pancreas and anterior pituitary
  • Trypanosoma Brucei

    Parasitic agent that causes African Sleeping Sickness, a type of trypanosomiasis. med after Dr. Brucei

  • Causes sleepiness and recurring fever
  • Transmitted by the tsetse fly
  • Endemic to subSaharan Africa.
  • Trypanosoma Cruzi

    Parasitic agent that causes Chagas disease. med after Dr. Cruz

  • Roma's sign (unilateral periorbital swelling without pain)
  • Dilated cardiomyopathy
  • Megacolon and megaesophagus
  • Transmitted by the Reduviid (or kissing) bug
  • Ubiquitinproteasome degradation

    Method of destroying proteins using a "protein" complex; target proteins are tagged by another protein that is "present" in almost every eukaryotic tissue.

    • Ubiquitous (English) - Present, Found everywhere
    • In (Unknown) - To carry off by evacuation
    • Protein (English) - A compound composed of amino acids
    • Soma (Greek) - Body
    • Degrader (French) - Degrade, deprive
  • Defects in the ubiquitinproteasome system have been implicated in some cases of Parkinson disease
  • Ubiquitinproteasome degradation is essential for proper functioning of the cell cycle, response to oxidative stress and gene expression
  • Uniparental disomy

    A type of genetic transmission where the offspring receives "two" genetic "bodies" from "one" "ancestor" or parent.

    • Unus (Latin) - One
    • Parentem (Latin) - Farther or mother, ancestor
    • Di (Greek) - Two, Double, Twice
    • Soma (Greek) - Body
  • Uniparental disomy of chromosome 15 is one of the mechanisms that cause PraderWilli or Angelman syndrome
  • The first reported clinical case of UPD was in 1988 and involved a girl with cystic fibrosis and short stature who had two maternal copies of chromosome 7