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Penem (English) - Medication Naming Convention
2 terms share this root
Imipenem/Cilastin

Carbapenem

  • Penem (English) - Medication Naming Convention
  • Susceptible aerobic and aerobic grampositive and gram negatice organisms
  • Imipenem binds to penicillinbinding proteins and inhibits bacterial cellwall synthesis
  • It is rapidly degraded by rel dehydropeptidase I so it is given in combition with cilastatin, a DHPI inhibitor, to increase imipenem's half life and tissue penetration.
  • Meropenem

    Carbapenem

    • Penem (English) - Medication Naming Convention
  • Grampositive, gramnegative( including Pseudomos) and anerobic bacteria
  • Complicated skininfections, intraabdomila infections and bacterial meningitis
  • Inhibits bacterial cell wall synthesis, however it is highly resistant to degradation by betalactamases or cephalosporises
  • Unlike imipenem, it is not degraded by DHPI so can be given without cisplastin

  • Mnemonics
    Uh Oh! Erta' Betta' Geta' 'nother antibiotic!
    -Penem that does not work for Pseudomonas Treatment
    Ertapenem is the only -penem that does not have Pseudomonas coverage
    MEDYMOLOGY