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Blastos (Greek) - Germ, sprout, bud or budding, immature
29 terms share this root
Acute lymphoblastic leukemia

A "sharp" or quickly onset "mass" of "budding" or immature "white" blood cells in the "blood". The sharp onset does not refer to the time of onset, but the time within the cell development, in this case, even more immature cells.

  • Acuere (Latin) - To Sharpen, sharply onset
  • Lympha (Latin) - Water, clear water, a goddess of water
  • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Leukos (Greek) - White, clear
  • Haima (Greek) - Blood
  • Leukemia seen more in children under 15 that involves an overproductions of either B or T lymphoblast (>20 % in bone marrow)
  • TdT positive
  • BALL is CD10+, CD19+, CD20+
  • BALL requires prophylactic chemotherapy to the scrotum and CSF
  • TALL is CD10 and presents as a thymic mass in teenagers
  • Increased incidence in Down Syndrome
  • Can be seen with the Philadelphia chromosome mutation
  • Ameloblastoma

    A benign "mass" composed of "enamel"producing "germ" cells

    • Amelo (English) - Emel
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • An odontogenic tumor comprised of ameloblasts
  • Usually occur in the posterior regions of the mandible
  • Most common in males in the 4th decade
  • Can be locally aggressive and invasive
  • Typically have a 'honey comb' or 'soap bubble' radiographic appearance
  • Ameloblasts

    Cell which "germinates" tooth "enamel"

    • Amelo (English) - Emel
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Ameloblasts are cells which form enamel. They secrete enamel proteins amelin and amelogenin. These proteins mineralize to become enamel.
  • Osteoblasts form bone. Ameloblasts form enamel.
  • Androblastoma

    A "mass" of "budding cells" that produce hormones that "make a man".

    • Andro (Greek) - Man, male
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • A sex cord tumor of the testicles and ovaries
  • Produces high amounts of testosterone leading to masculine features in women
  • Acne
  • Hirsutism
  • Also known as a Sertolileydig tumor, as the etymology suggests, the me tumor secretes testosterone making women appear masculine.
  • Blastic

    Refers a certain amount of "buds", germs, cells or cell layers.

    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    Blastocyst

    A "pouch"like structure formed in early development with an inner "budding" cell mass that makes the embryo and an outer layer (trophoblast) that gives rise to the placenta.

    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Kustis (Greek) - Bladder, atomical pouch or sac
  • Blastocyst begins to form 5 days after fertilization
  • Blastomyces Dermatitidis

    "Budding" "fungus" that causes lesions to form in capillary beds throughout the body, including the "skin".

    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Mukes (Greek) - Fungus, mushroom
    • Derma (Greek) - Skin
  • Dimorphic fungi found in soil along the Ohio and Mississippi River valley and Great Lakes regions
  • Large round yeast with single broad base buds and a doubly refractile wall
  • Can cause pneumonia in immunocompetent people and disseminated infection in immunocompromised people.
  • Blastula

    A hollow sphere of "budding, or sprouting" cells in a developing embryo.

    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • A hollow sphere of cells produced during embryogenesis
  • Cementoblastoma

    A "tumor" of cementoblasts (cells which "germinate" "cementum")

    • Caementum (Greek) - Rough stone
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • This tumor is a round mass of cementum or cementumlike tissue growing out of a tooth root. It contains cementoblasts.
  • Radio graphically it is radiopaque, wellcircumscribed, and encircled by a radiolucent border. It may have a sunburst appearance.
  • Cementoblasts

    Cells which "germinate" "cementum"

    • Caementum (Greek) - Rough stone
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Cementoblasts are cells which form cementum. They do so by laying down an organic matrix made of collagen, sialoprotein, and osteocalcin. The saliva contains minerals which then mineralize this matrix into cementum.
  • Like osteoblasts which form bone, cementoblasts form cementum
  • Cytotrophoblast

    A "germ" "cell" of the placenta that "consumes" nutrients from blood for fetus.

    • Cytos (Greek) - Cell, A Hollow, Receptacle, Vessel
    • Trophe (Greek) - Food, Nourishment
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Inner layer
  • Trophoblast
  • The inner layer of the trophoblast in an embryonic placenta that gives rise to the syncytiotrophoblast that make up the outer layer.
  • Desmoplastic ameloblastoma

    A rare, "fastened," benign "formation/tumor" of the "enamel" cell "buds" (i.e. the odontogenic epithelium)

    • Desmos (Greek) - Bond, Chain, Fastening
    • Plassein (Greek) - To mold or form
    • Amelo (English) - Emel
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • One of the 6 histopathological subtypes of Ameloblastoma
  • Has a mixed lucentopaque radiographic appearance
  • Represents about 9% of all ameloblastomas encountered
  • Epiblast

    A cell type that "sprouts" from the inner cell mass of the blastocyst and lies "above" the hypoblast.

    • Epi (English) - Above, Upon
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Undergoes gastrulation to form the three germ layers (ectoderm, mesoderm, endoderm)
  • Literally med above the bud because it lies above the hypoblast.
  • Glioblastoma multiforme

    • Glia (Greek) - Glue
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
    • Multus (Latin) - Much, many
    • Forma (Latin) - Form
  • Ringenhancing lesions
  • Seen in adults more so than children
  • Butterfly lesion that crosses the corpus callosum
  • Pseudopalisading necrosis
  • The me is derived from the fact that this type of tumor arises from glial cell precursors and causes necrosis, cyst like structures and bleeding hence the me multiforme.
  • Hemangioblastoma

    CNS "tumor or mass" that originates from "budding" cells of "blood vessels".

    • Haima (Greek) - Blood
    • Angeion (Greek) - A vessel, receptacle
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • Associated with VHL syndrome
  • May produce EPO
  • Hypoblast

    "Germ" cells located "under" the epiblast within a developing blastocyte.

    • Hypo (Greek) - Under, beneath, less
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Gives rise to the endoderm (respiratory tract and digestive tract)
  • Medulloblastoma

    A "growth" of "budding cells" from the "marrow or pith" in the brain.

    • Medulla (Latin) - Bone marrow, pith
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • Highly malignant
  • Shows drop metastases, homerwright rosettes, small blue cells
  • Causes hydrocephalus
  • Neuroectodermal origin
  • Megaloblastic

    Type of anemias in which "budding cells" are "larger" than normal due to impaired D synthesis.

    • Megalo (Greek) - Great, large
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Usually due to B12 or folate deficiency
  • Megaloblastic anemia

    Type of anemias in which "budding cells" are "larger" than normal due to impaired D synthesis leading to being "without" proper "blood" composition.

    • Megalo (Greek) - Great, large
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • An (Greek) - Without, not
    • Haima (Greek) - Blood
  • B12 or folate deficiency
  • Myeloblast

    Stem cell of "marrow" that "buds" into granulocytes (neutrophils, basophils, eosinophils).

    • Myelos (Greek) - Marrow, the brain
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • AML
  • Nephroblastoma

    Wilm's tumor "growth", the most common "kidney" cancer in children. Single sided "budding" flank mass in a child that does not cross the midline.

    • Nephros (Greek) - Kidney
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • WAGR complex: Wilms' Tumor, Aniridia, GU malformation, Retardation
  • The second most common palpated mass in a child behind a distended urinary bladder
  • Neuroblastoma

    Abdominal "growth" that "buds" over the midline. Can be found anywhere along the sympathetic "nerve" chain ganglia.

    • Neuron (Greek) - Nerve, straw, tendon
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • Bombesin tumor marker
  • Nmyc oncogene activation
  • Most common adrenal medulla tumor in children
  • Odontoblasts

    Cells that originally "bud" from neural crest cells, that eventually function to form the dentin of the "teeth."

    • Odous (Greek) - Tooth
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Neural crest cell derivative
  • Osteoblast

    Cells that synthesize "bone" that originally came from mesenchymal "germ" cells.

    • Osteon (Greek) - Bone
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Osteoid (bony matrix) is mineralized by osteoblasts
  • Osteoblastic metastasis

    The spread of cancer to "bone" "beyond" its originally cancerous organ possibly leading to "budding" of new "bone" in "places" causing bone restructuring.

    • Osteon (Greek) - Bone
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Meta (English) - Beyond, in the midst of
    • Histanai (Greek) - To place, cause to stand, to stop
  • Prostate cancer
  • Ringed sideroblast

    An "immature, budding" red blood cell with a "ring" of excess of "iron" in its mitochondria.

    • Ring (Olde English) - Small circlet
    • Sidero (Latin) - Iron, Constellation
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Seen in sideroblastic anemia
  • Visualized by the Prussian Blue stain
  • Sideroblastic anemia

    A condition of being "without" "blood" because "budding" cells contain "constellations" of iron, preventing it from being used in red blood cells.

    • Sidus (Latin) - Constellation
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • An (Greek) - Without, not
    • Haima (Greek) - Blood
  • A defect in the enzyme aminolevulinic acid synthase, leading to decreased heme synthesis. Characterized by ringed sideroblasts and increased iron and ferritin levels. Treated with pyridoxine.
  • Defective ALA synthase
  • Ringed sideroblasts
  • Pyridoxine treatment

  • Mnemonics
    These conditions make your red blood cells small really F. A. S. T.
    The Causes of Microcytic Anemia
    Fe (iron) deficiency anemia. Anemia of chronic Disease. Sideroblastic Anemia. Thalassemia
    Syncytiotrophoblast

    A type of "budding" "cell" found within the placenta that is involved in "nourishment" of the developing fetus.

    • Syn (Greek) - With, together
    • Trophe (Greek) - Food, Nourishment
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
  • Syncytial layer prevents maternal immune cells from reaching embryo
  • Unicystic ameloblastoma

    A benign "mass" composed of "enamel"producing "germ" cells that appears as “one” “pouch” radio graphically

    • Uni (Latin) - One
    • Kustis (Greek) - Bladder, atomical pouch or sac
    • Amelo (English) - Emel
    • Blastos (Greek) - Germ, sprout, bud or budding, immature
    • Oma (Greek) - Morbid growth, mass, tumor
  • An odontogenic tumor comprised of ameloblasts
  • Usually occur in the posterior regions of the mandible
  • Typically appears multilocular although unilocular or unicystic appearances are not uncommon either
  • MEDYMOLOGY